Zoloft (sertraline) is an antidepressant belonging to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Sertraline affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms. Zoloft is used to treat depression, obsessive-compulsive disorder, panic disorder, anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD). Zoloft may also be used for purposes not listed in this medication guide. You should not use Zoloft if you also take pimozide, or if you are being treated with methylene blue injection. Do not use Zoloft if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Some young people have thoughts about suicide when first taking an antidepressant. Report any new or worsening symptoms to your doctor. The study - conducted in nonhuman primates with brain structures and functions similar to those of humans - found that the antidepressant sertraline, a selective serotonin reuptake inhibitor (SSRI) marketed as Zoloft, significantly increased the volume of one brain region in depressed subjects but decreased the volume of two brain areas in non-depressed subjects. "These observations are important for human health because Zoloft is widely prescribed for a number of disorders other than depression," said Carol A. D., professor of pathology-comparative medicine at Wake Forest Baptist and lead author of the study, published in the current online issue of the journal Neuropharmacology. In the study, 41 middle-aged female monkeys were fed a diet formulated to replicate that consumed by many Americans for 18 months, during which time depressive behavior in the animals was recorded. Female monkeys were chosen for this study because depression is nearly twice as common in women as men and the use of antidepressants is most common in women ages 40 to 59. After the 18-month pre-study phase, the monkeys were divided into two groups balanced for body weight, body mass index and depressive behavior. For the next 18 months, 21 monkeys received sertraline in daily doses comparable to those taken by humans while a group of 20 received a placebo. This treatment regimen is analogous to a human taking an antidepressant for approximately five years. Xanax bar Side effects of clomid Valacyclovir dosing for shingles Buy prednisone overnight delivery DESCRIPTION. ZOLOFT contains sertraline hydrochloride, an SSRI. Sertraline hydrochloride has a molecular weight of 342.7 and has the following chemical. Statistics even reveal that in 2013, Zoloft sertraline was the most prescribed antidepressant in the United States. While many people have found that Zoloft. May 14, 2012. inhibitors SSRIs, such as fluoxetine Prozac and sertraline Zoloft. “If you aren't taking an extended-release tablet, you can try taking the. Zoloft (sertraline) is one of the most popular selective serotonin reuptake inhibitors (SSRIs). Statistics even reveal that in 2013, Zoloft (sertraline) was the most prescribed antidepressant in the United States. While many people have found that Zoloft (sertraline) is a particularly effective medication, others have responded poorly to the medication and ended up experiencing a variety of complications. Because of these complications, some patients decide to quit using the medication. Withdrawal from Zoloft (sertraline), however, can be a difficult process, so there are some important pieces of information that a person should know. Zoloft (sertraline) is not one of the controlled substances on the list of scheduled substances. As a result, some sites sell Zoloft to patients without the requirement of a valid prescription. Determining if you should take your antidepressant at night or in the morning depends on the specific medication you're taking, its side effects, and how it influences your quality of life. Your prescribing doctor may suggest a specific time of day for you to take your antidepressant to minimize any common adverse effects—primarily insomnia or drowsiness—that may be associated with your particular prescription. Some antidepressants—such as Celexa (citalopram), Zoloft (sertraline), and Effexor (venlafaxine)—have sustained-release formulations, and do not appear to be any more or less effective when taken at varying times of the day. However, some selective serotonin reuptake inhibitors (SSRIs), the class to which these medications belong, can disrupt sleep for some people and would be best taken in the morning. For example, the manufacturer of Prozac (fluoxetine) recommends it be taken in the morning because it can make some people feel more energized, especially at the beginning of treatment. On the other hand, when Prozac is given in combination with Zyprexa (olanzapine)—a combination called Symbyax—as a therapy for treatment-resistant depression, it's recommended to be taken in the evening as it can cause sleepiness. Paxil (paroxetine) is also generally taken in the morning in order to prevent sleeplessness at night. Zoloft extended release Zoloft Sertraline Hcl Side Effects, Interactions., Zoloft Sertraline How Long Does It Stay In Your System? The. Where to order celebrex Zoloft Should be taken with water. Sertraline may be taken with or without food. Prozac An extended-release Prozac capsule should not be broken, chewed, or opened. The pill should be swallowed whole as it is designed to release medicine slowly in the body. Prozac vs Zoloft - Difference and Comparison Diffen. Will Antidepressants Wreck Your Sex Life? - Depression Center.. Is Zoloft Extended Release -. For level 2, the primary comparisons were among the three medication switches sustained-release bupropion, sertraline, and extended-release venlafaxine, which are discussed in this report, and. Sep 4, 2015. A commonly prescribed antidepressant may alter brain structures in depressed and non-depressed individuals in very different ways, according. Compare Zoloft vs. Wellbutrin Head-to-head comparisons of medication uses, side effects, ratings, and more. Wellbutrin Prescription only. Improves mood and helps you relax. Zoloft sertraline is good for treating depression and anxiety, but it can interact with many medicines. Extended release; Price. Lowest price. $8.63. Find instant.