Duloxetine pregnancy

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    Duloxetine pregnancy


    The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Listing a study does not mean it has been evaluated by the U. This is an observational, exposure-registration and follow-up registry. based Registry designed to monitor women who are exposed to Cymbalta (duloxetine) during pregnancy. If your browser does not accept cookies, you cannot view this site. There are many reasons why a cookie could not be set correctly. Below are the most common reasons: This site uses cookies to improve performance by remembering that you are logged in when you go from page to page. To provide access without cookies would require the site to create a new session for every page you visit, which slows the system down to an unacceptable level. This site stores nothing other than an automatically generated session ID in the cookie; no other information is captured. In general, only the information that you provide, or the choices you make while visiting a web site, can be stored in a cookie. For example, the site cannot determine your email name unless you choose to type it.

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    Background Duloxetine hydrochloride is approved for the treatment or management of major depressive disorder, generalized anxiety disorder. The Safety of Duloxetine During Pregnancy and Lactation. Chittaranjan Andrade, MD. Clinical Problem. Ms K is a 29-year-old woman with a 7-year history of. This drug is not approved for use during pregnancy. Cymbalta should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

    Animal studies have revealed evidence of teratogenicity. If treating pregnant women with duloxetine during the third trimester, the physician may wish to consider tapering this drug. Neonates exposed to SSRIs and SNRIs late in the third trimester have uncommonly reported clinical findings including respiratory distress, cyanosis, apnea, seizures, temperature instability, feeding difficulty, vomiting, hypoglycemia, hypotonia, hypertonia, hyperreflexia, tremor, jitteriness, irritability, and constant crying. These effects have mostly occurred either at birth or within a few days of birth. These features are consistent with either a direct toxic effect of SSRIs and SNRIs, or possibly a drug discontinuation syndrome; in some cases, the clinical picture is consistent with serotonin syndrome. Epidemiological data have suggested that the use of SSRIs, particularly in late pregnancy, may increase the risk of persistent pulmonary hypertension in the newborn. To monitor the outcomes of pregnant women exposed to this drug, a pregnancy registry has been established. Healthcare providers are encouraged to register patients by calling the Cymbal (R) Pregnancy Registry at 1-866-814-6975 or by visiting AU TGA pregnancy category B3: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. If you have untreated depression, you might not seek optimal prenatal care or eat the healthy foods you and your baby need. Experiencing major depression during pregnancy is associated with an increased risk of premature birth, low birth weight, decreased fetal growth or other problems for the baby. Unstable depression during pregnancy also increases the risk of postpartum depression, early termination of breast-feeding and difficulty bonding with your baby. A decision to use antidepressants during pregnancy is based on the balance between risks and benefits. Overall, the risk of birth defects and other problems for babies of mothers who take antidepressants during pregnancy is very low. Still, few medications have been proved safe during pregnancy and certain types of antidepressants have been associated with a higher risk of complications for babies. If you use antidepressants during pregnancy, your health care provider will try to minimize your baby's exposure to the medication.

    Duloxetine pregnancy

    Pregnancy and Antidepressants - WebMD, The Safety of Duloxetine During Pregnancy and Lactation - E-lactancia

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  3. Sep 15, 2008. Safety of Psychiatric Medications During Pregnancy and Lactation. Duloxetine Cymbalta. C. NA. NA. Mirtazapine Remeron. C. NA. L3.

    • ACOG Guidelines on Psychiatric Medication Use During Pregnancy..
    • The Cymbalta® Pregnancy Registry Home.
    • Low dose Cymbalta during pregnancy and breastfeeding - InfantRisk..

    Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor antidepressant SSNRI. Duloxetine affects chemicals in the brain that may be unbalanced in people with depression. Duloxetine is used to treat major depressive disorder in adults. It is also used to treat general anxiety disorder in adults and children who are at least 7 years old. Oct 5, 2015. Comparatively, pregnancy data on the newer combined serotonin/noradrenaline receptor inhibitors SNRI, venlafaxine and duloxetine, are. Jun 25, 2015. Duloxetine - Get up-to-date information on Duloxetine side effects, uses, dosage, overdose, pregnancy, alcohol and more. Learn more about.

     
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